Ketamine is lumped into the same category as psychedelics but it works differently than classical psychedelics like psilocybin or LSD. Ketamine relaxes chandelier cells in the brain, which control pyramidal cells. The pyramidal cells are the “thinking” cells and pass on messages to other neurons. By relaxing that grip, ketamine can produce a dissociative effect; a person can feel “floaty” or like they’re in a different reality
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